Reducing mortality in hip fracture patients using a perioperative approach and “Patient- Centered Medical Home” model: a prospective cohort study
© Graham et al.; licensee BioMed Central Ltd. 2014
Received: 4 December 2013
Accepted: 22 January 2014
Published: 3 February 2014
Hip fracture patients experience high morbidity and mortality rates in the first post-operative year after discharge. We compared mortality, utilization, costs, pain and function between two prospective cohorts of hip fracture patients, both managed with identical perioperative protocols and one group subsequently managed via a “Patient-Centered Medical Home” (PCMH) primary care management model.
We analyzed 6 and 12-month outcomes from two matched cohorts of patients who were surgically treated for hip fracture from January 1, 2010 to June 30, 2011 at two hospitals (n = 194). Controls did not receive PCMH and were matched to cases on surgery date, sex, age, and comorbidities. Mortality and healthcare utilization were the primary outcomes studied, with medical costs, quality of life, pain and function at 12 months assessed as secondary outcomes in a subgroup. Survival analysis, regression and Student-t testing were used with p < 0.05 considered significant.
At 6 months, PCMH patients had significantly lower mortality than patients receiving standard care (11% vs. 26%, p < 0.01). At 12 months, a difference persisted (23% vs. 30%, p = 0.12) but was no longer statistically significant. Mean quality of life scores were similar (0.73 vs. 0.76, p = 0.49) and Harris Hip score was slightly improved for PCMH (73 vs. 64, p = 0.04). Mean costs per patient per month were lower for PCMH but not significantly different ($69 vs. $141, p = 0.20 for pharmacy costs; $1212 vs. $1452, p = 0.45 for non-pharmacy costs).
Patients receiving aggressive post-discharge care from a PCMH program showed significant benefits in terms of reduced mortality at 6 months, with similar costs and functional outcomes at 12 months. PCMH was not shown to improve all outcomes studied, but these results suggest that ongoing Medical Home management can have some benefit for patients without negatively impacting function or cost.
KeywordsHip fracture Mortality Care coordination Primary care
Hip fractures remain a major challenge to health care systems throughout the world , as both the number of hip fracture patients and the costs associated with their care increase over time [2–6]. Despite improvements in implant technology, morbidity and mortality rates in the first postoperative year remain high . Numerous reports have shown that perioperative approaches that include medical optimization, multidisciplinary care and rehabilitation decrease immediate perioperative morbidity . However, the significant morbidities and costs associated with hip fractures more often occur after discharge and are related to long-term management of medical comorbidities . Further complicating matters, it is difficult to distinguish between morbidity related to the hip fracture itself as opposed to the overall frailty and vulnerability of the elderly population . In theory, an optimal approach to managing patients would initially optimize the patient for surgery, match implants to the patients’ functional condition, and subsequently manage the patient’s overall health status including existing comorbidities. This multimodal approach has not been previously reported in the orthopaedic literature. If this approach successfully decreased readmissions and mortality, any increased costs associated with more aggressive post-operative management might be offset within a health system .
At the same time that hip fractures challenge the orthopaedic community, there are recognized shortcomings in hospital post-discharge transitions of care in general. As recently as 2009, half of Medicare fee-for-service patients who had a 30-day readmission did not visit their physician before being readmitted . Communication gaps are suspected to account for a significant share of readmissions, and these occur between providers (e.g., discontinued prescriptions), between provider and patient (e.g., lack of patient education) and in transitions between the hospital and community setting [13–15]. Systematic reviews have reported significant reductions in 30-day readmission rates and cost savings associated with several enhanced discharge processes, most of which used enhanced in-hospital communication, payment incentives, and other multimodal approaches [16–18].
The Patient-Centered Medical Home (PCMH) model, which evolved from the Chronic Care Model , involves enhancing the role of primary care providers as the locus of care coordination. The PCMH is not a physical location, but a redesign of healthcare delivery to facilitate partnerships among an individual patient and his/her personal physician and family, all supported by resources including enhanced information systems and communications infrastructure. The American Academy of Pediatrics (AAP), American Academy of Family Physicians (AAFP), and other societies representing approximately 330,000 U.S. physicians describe 7 joint principles of the PCMH. These principles include each patient having an ongoing relationship with his/her personal physician, highly coordinated care, enhanced access to care, and payment structures that reflect the value of care management work . At our health system, a PCMH model attempts to reduce post-discharge morbidity by using nurse case managers to coordinate the transition from hospital to home. Case managers use early telephone outreach, medication reconciliation, social support assistance, and ensure timely follow-up with primary care physicians in the month immediately following surgery.
We compared rates of mortality, hospitalizations, emergency department visits and prescription orders between two prospective cohorts of hip fracture patients, both managed with identical perioperative protocols and one group subsequently managed via PCMH. Costs, functional outcomes and quality of life were also studied as secondary outcomes in a smaller subsample. We hypothesized that the best outcomes would occur in patients managed initially with a standardized approach and subsequently with PCMH management.
This was a prospective, non-randomized two-cohort study conducted at two level-1 trauma centers within Geisinger Health System (GHS), a large integrated health system located in Pennsylvania. GHS serves a 41-county area with approximately 2.5 million people, employs a total of 800 physicians including 200 primary care physicians, and operates 41 outpatient clinics and five hospitals. The average duration of care for patients in the system exceeds ten years, and an electronic health record has been the sole-source ambulatory record for all patients since 2001. The Department of Orthopaedics also maintains a prospective trauma registry in which all treated fractures are recorded and classified according to the AO/Orthopaedic Trauma Association (AO/OTA) radiographic system.
Beginning in 2006, GHS implemented a “Patient-Centered Medical Home” (PCMH) program, referred to as “ProvenHealth Navigator®”. This program has been described in detail elsewhere [21, 22]. This PCMH model represents a partnership between the health system and an affiliated insurance provider (Geisinger Health Plan) and is comprised of several parallel initiatives to improve overall quality of care. The primary element of interest for this study is that office-based nurse case managers (CMs) are hired by the insurance provider and integrated into the clinical care team at specific primary care sites. These CMs focus on coordinating services for at-risk patients who belong to that clinic, and they provide early outreach and close follow-up for patients who are transitioning home after a hospital discharge for any reason including hip fracture surgery . Quality measurement and reporting encourage adherence to evidence-based care guidelines, and practices and individual physicians are paid additional stipends and can share in estimated savings, subject to meeting quality goals. No additional stipends at any site were tied directly to this particular study.
During the transition period of 2006–2011, the PCMH program was introduced to 41 clinic sites in phases. Although the order of site enrollment was not randomized, clinic sites were geographically dispersed and neither individual physicians nor patients could choose whether to participate in the PCMH program. Thus, the transition period provided an opportunity for a natural experiment to examine clinical outcomes of patients undergoing hip fracture surgery who could be categorized as either PCMH or non-PCMH according to the clinical site where their primary care physician was located. This study was approved by the Geisinger Institutional Review Board (IRB).
All patients aged 60 or over who presented to either of two hospitals with an isolated closed, acute proximal femur fracture and were surgically treated from January 1, 2010 to June 30, 2011 were enrolled in this study. Acute fractures were defined as fractures sustained within 48 hours prior to presentation, and proximal femur fractures were defined as fractures diagnosed by plain radiography and classified as AO/OTA fractures 31-A (trochanteric) or 31-B (neck) by the attending surgeon on call. Patients were excluded if they sustained fractures that were open, high energy, related to osteomyelitis or neoplastic disease, or radiographically occult. Patients were also excluded if they presented in a moribund state, where any consideration of surgical treatment was deemed inappropriate, or if they elected to be treated non-operatively.
Overview of perioperative and post-discharge protocol for all patients in the study
Perioperative management (All patients)
Post-discharge management (All patients)
Medical home management (Patient-Centered Medical Home patients only)
1. Perioperative risk assessment and management
1. Follow-up with High-Risk Osteoporosis Clinic (if needed)
1. Nurse Case Manager (CM) makes initial call to patient within 24–48 hours of hospital discharge.
2. Timing of surgical intervention
2. Continuation of aggressive physical therapy
3. Prophylactic antibiotics
4. Thromboembolic prophylaxis
3. Deep venous thrombosis (DVT) Prophylaxis
2. CM reviews medication list with patient.
5. Prevention and management of delirium
4. Wound check, functional evaluation, and radiographic examination at 6 weeks
3. CM ensures that follow-up visit is scheduled with primary care provider within 7 days.
6. Prevention of decubitus ulcers
7. Prevention of Constipation
8. Physical therapy intervention
5. Periodic assessment (no less than every 3 months) until a baseline functional state or death occurs
4. CM ensures that a patient-specific action plan is in case if patients have any trouble.
9. Assessment for underlying osteoporosis
10. Appropriate discharge placement
5. Patients receive weekly calls (2–3 minutes) for 4 weeks, to ask about complications or areas that need follow-up from CM.
Questions asked via telephone questionnaire to surviving patients at 12 months follow-up
EQ-5D quality-of-Life (EuroQOL) index questions (respondent chooses one answer)
Harris hip score pain/function subsection (response choices not shown)
I have no problems in walking about.
How would you describe your hip pain?
I have some problems in walking about.
I am confined to bed.
I have no problems with self-care.
How much support do you need when walking?
I have some problems washing or dressing myself.
I am unable to wash or dress myself.
3. Distance Walked
3. Usual activities
How much are you able to walk?
I have no problems with performing my usual activities.
I have some problems with performing my usual activities.
I am unable to perform my usual activities.
Do you walk with a limp?
I have no pain or discomfort.
I have moderate pain or discomfort.
Are you able to put on your own shoes and socks?
I have extreme pain or discomfort.
I am not anxious or depressed.
Are you able to climb stairs?
I am moderately anxious or depressed.
7. Public transportation
I am extremely anxious or depressed.
Are you able to board a bus?
6. Quality-of-life scale question
To help people say how good or bad a health state is, imagine a scale on which the best state you can imagine is marked 100 and the worst state you can imagine is marked 0. We would like you to indicate on this scale how good or bad your own health is today, in your opinion.
Are you able to sit comfortably?
The primary endpoint for this study was all-cause mortality following hip fracture surgery, and so we used nonparametric survival analysis to compare survival between the two cohorts at 6 and 12 months. Secondary endpoints were rates of inpatient hospitalizations, emergency department visits, and prescription orders during the 6 and 12 months following surgery, which were compared using Poisson regression. Finally, as tertiary endpoints, we used Student-t testing to compare mean medical costs (pharmacy, non-pharmacy and total) at 6 and 12 months, and questionnaire scores among responders at 12 months. Costs were normalized to set the PCMH group’s mean monthly pharmacy cost to $100 in order to protect business-sensitive information. For all analyses, generalized estimating equation (GEE) methods were used to cluster observations to account for the matching of subjects described below. All statistical analysis was performed using SAS software (SAS 9.2, Cary, NC) with differences at p < 0.05 considered statistically significant.
This study was non-randomized, and although PCMH assignment depended only on the geography of the clinic sites and not individual patient/physician preference, we recognized there could still be unbalanced confounding variables in the two groups. We therefore limited the analyses to a matched set of cases and controls. Each PCMH patient (case) was matched to one non-PCMH patient (control) based on surgery date (±90 days) and a propensity score to adjust for disease severity following the methods of Rosenbaum and Rubin [26, 27]. A logistic regression model calculated each patient’s propensity score (i.e., propensity for belonging to the PCMH group, on a scale of 0–1) using sex, age, Charlson Comorbidity Index, number of admissions and emergency department visits during the 12 months prior to surgery, and history of 10 comorbidities (hypertension, stroke, myocardial infarction, congestive heart failure, chronic kidney disease, other fractures, osteoporosis, anemia Alzheimer’s disease, and cancer). PCMH patients were excluded from analysis if they had propensity scores that did not overlap with any control patients, and cases were only matched to controls whose propensity scores fell within a tight caliper range in order to ensure balance between the cohorts . This matching procedure was performed on the entire study population to generate two matched cohorts for analysis of mortality/utilization outcomes (for which all subjects had available data), and then repeated to generate matched subgroups for cost (where only some patients had claims data) and functional outcomes (where only a subset of patients had survey responses at 12 months). Because of our strict inclusion/exclusion criteria limiting the study only to patients with a specific fracture type and operative treatment, further details of the fracture type or surgery were not used for matching.
Baseline characteristics of the case and control cohorts, after 1:1 matching based on date of surgery and propensity scoring method
Medical home cases (n = 97)
Controls (n = 97)
Age at surgery in years, Mean (SD)
Charlson comorbidity index, Mean (SD)
% Heart failure
% Renal disease
For the secondary analysis of healthcare costs, claims data were available for 66/108 (61%) of the PCMH patients and 42/195 (21%) of the non-PCMH patients. For the quality-of-life and pain/function telephone questionnaires administered to non-deceased patients at 12 months, the survey response rate was 41/82 (50%) for PCMH patients and 50/137 (37%) for non-PCMH patients. Repeating the matching procedure for the analysis of secondary outcomes yielded 15 matched pairs with cost data who survived 12 months (n = 30), and 35 matched pairs with pain/function data who survived 12 months (n = 70).
Outcomes at 6 and 12 months for the two cohorts, including mortality, hospitalizations, emergency department (ED) visits, prescription orders, and costs, with significant differences in bold
Medical home cases
N, subjects per group
N, Deaths at 6 months (%)
N, Deaths at 12 months (%)
N, matched subjects per group
Hospitalizations per 100 patients at 6 months
ED visits per 100 patients at 6 months
Prescription orders per patient at 6 months
Hospitalizations per 100 patients at 12 months
ED visits per 100 patients at 12 months
Prescription orders per patient at 12 months
Healthcare costs †
N, matched subjects per group
Mean pharmacy costs per patient-month (0–6 months)
Mean non-pharmacy costs per patient-month (0–6 months)
Mean total costs per patient-month (0–6 months)
Mean pharmacy costs per patient-month (0–12 months)
Mean non-pharmacy costs per patient-month (0–12 months)
Mean total costs per patient-month (0–12 months)
Quality of life and function at 12 months
N, matched subjects per group
Mean EQ-5D index*
Mean EQ-5D QOL scale**
Harris hip pain/Function score^
Our study demonstrates, in a prospective study of patients receiving a unified in-hospital protocol, that the addition of post-discharge care from a “Patient-Centered Medical Home” program, including a nurse case manager for primary care-based follow-up, was successful in significantly reducing mortality in the 6 months following hip fracture and showed evidence of benefits to hip pain and function as well. While it may be unrealistic to expect that such a post-discharge program would eliminate mortality/morbidity, this study makes a promising case for utilizing PCMH programs for a focused, limited period following discharge. Although significant benefits in reduced admissions, emergency department visits or medication utilization and costs were not seen, the two cohorts remained similar in these respects, suggesting that the aggressive follow-up by the PCMH program did not substantially drive up healthcare utilization or costs. Future larger-scale studies should help to better define the optimal patient population for such programs and refinements that would provide further benefits for patients undergoing hip fracture surgery. We note that, while we found more published estimates of 1-year mortality than 6-month mortality, our control group's 6-month and 12-month mortality rates of 26 and 30%, respectively, appear to be consistently in the range of the published findings of Johnston et al.  and others who have followed operative treatment of hip fractures.
Mortality and morbidity after hip fracture in elderly patients remains a serious problem; however, there is growing evidence to suggest that patient factors and specific details of the approach to post-fracture treatment can impact mortality and quality of life. As noted by Johnston et al., many studies report mortality following hip fracture as a simple percentage and do not take into account age, gender and other factors . In a recent systematic review, Butler et al. concluded that while neither implant type nor surgical approach were associated with differences in mortality rates, patient factors such as age, sex, pre-fracture functioning, and cognitive impairment were directly related to mortality and functional outcomes . This literature suggested that the main mortality risk for elderly women is in the 6 weeks following surgery, while the risk for men is higher near 6 months, with comorbidities and age impacting different subgroups. In a study that complements our current results in a different population, Rahme et al. retrospectively reviewed 11,326 patients receiving hemiarthroplasty for hip fracture and showed that the small percentage of those (16%) who received post-discharge home care had a lower mortality rate at 3 months than those who received no home care . While the data collected for this study do not allow us to pinpoint the exact reason why the PCMH program influenced the 6-month mortality rate in our study, we believe that by providing reinforcement during the critical 4 weeks following discharge, the primary care PCMH team may be able to better engage, activate and educate patients as well as identify and resolve issues that may otherwise be missed or caused by care gaps during the transition from hospital to home.
The main strengths of our study are its population and statistical design. We were able to use patients in an integrated health system where electronic health records were available for the hip fracture population to quantify mortality, inpatient admissions, emergency department visits and other healthcare utilization. Furthermore, we were able to take advantage of the fact that a PCMH program was in the middle of being implemented such that patients would naturally be assigned to either an intervention group (PCMH) or control group for post-discharge care. Finally, we employed robust statistical methods to identify and balance confounding variables in the two cohorts through matching. The chief limitations of the study are the modest sample size and the fact that it was a non-randomized study, though we took steps to address biases due to confounding through the matched study design. Nevertheless, not all subjects could be appropriately matched to controls, resulting in a further reduced sample size. We note, for example, that the number of deaths between 6 and 12 months was small, and with a larger sample size, some of the nonsignificant findings here may also have reached statistical significance. For the secondary outcomes of cost and functional questionnaires, we also note that not all subjects responded to the telephone questionnaire or had the appropriate insurance provider that allowed us to measure costs. Finally, the questionnaires were administered at 12 months only and we did not collect preoperative scores, though we expect that acute injury patients would have both EQ-5D and functional scores similar to the general population in their own age range, on average. While we took advantage of the data collection methods of an integrated health system (EHR tracking, claims data, survey center) to perform this investigation, we note that standardized protocols and PCMH models are increasingly being adopted across the U.S. and we believe that these results should be highly translatable to a variety of healthcare settings.
Increasingly, society, patients and payors are demanding measurable quality outcomes. The biggest social impacts may be made by improving the outcome of patient groups whose injuries significantly affect society, such as the elderly patients who sustain hip fractures. Given the multitude of different implant studies which have shown little difference in one-year outcomes for this common yet socially-disruptive injury, studies like this one suggest that the patient care that takes place outside the operating room may ultimately have the biggest impact on improved outcomes. The biggest improvements thus far in hip fracture care have not come from changes in implant technology (e.g., switching to a locked side plate or to an intramedullary device) , but from multidisciplinary management of these patients in the acute setting; longer-term benefits of these in-hospital interventions, however, have not been widely demonstrated [32–34]. It is our hope that the current study provides new evidence regarding important patient outcomes and costs, comparing an intrinsic control group with an experimental group, and that future work will support compelling arguments to government and private payors that the most cost-effective standard of care also gives the highest quality outcome. We recognize that the majority of care-coordination efforts thus far have focused on chronic diseases such as congestive heart failure or diabetes, and that evidence of effectiveness has been mixed, depending on the specific features of the intervention [35–38]. Future work should determine which specific conditions yield high-value results in order to avoid the error of a one-size-fits-all approach.
Patients receiving aggressive post-discharge care from a “Patient-Centered Medical Home” program showed significant benefits in terms of reduced mortality, improved function, and trends toward reduced medical costs in the time period following hip fracture. Future studies with larger cohorts of PCMH patients are highly encouraged in order to reinforce these results and further examine the details of how PCMH may or may not benefit individual patients. Post-surgical care of elderly, multi-comorbid patients is complex, but these results suggest that ongoing PCMH management can benefit patients in the critical period immediately following a hip fracture and surgery.
A HIPAA waiver of authorization and consent was granted for the retrospective review of records for this study. A partial waiver of authorization and consent was granted for prospectively identifying patients for follow-up questionnaires over the telephone, and completing the telephone survey implied verbal consent on part of the patient.
This project was funded by a 2010 grant from the Orthopedic Trauma Association. The authors would also like to thank: Janet Tomcavage and her team at Geisinger Health Plan for consultation, planning and acquisition of claims data; and David Nevius and the Geisinger Survey Call Center team for administration of the telephone surveys. Earlier versions of this work were presented at the annual conferences of the Orthopaedic Trauma Association (OTA) in Minnesota, MN, October 3–6, 2012 and the American Academy of Orthopedic Surgeons (AAOS) in Chicago, IL, March 19–23, 2013.
- Johnell O, Kanis A: An estimate of the worldwide prevalence, mortality and disability associated with hip fracture. Osteoporos Int. 2004, 15: 897-902. 10.1007/s00198-004-1627-0.View ArticlePubMed
- Abrahamsen B, Van Staa T, Ariely R, Olson M, Cooper C: Excess mortality following hip fracture: a systematic epidemiological review. Osteoporos Int. 2009, 20: 1633-1650. 10.1007/s00198-009-0920-3.View ArticlePubMed
- Bentler SE, Liu L, Obrizan M, Cook EA, Wright KB, Geweke JF: The aftermath of hip fracture: discharge placement, functional status change, and mortality. Am J Epidemiol. 2009, 170: 1290-1299. 10.1093/aje/kwp266.PubMed CentralView ArticlePubMed
- Brauer CA, Cocaperraillon M, Cutler DM, Rosen AB: Incidence and mortality of hip fractures in the United States. JAMA. 2009, 302: 1573-1579. 10.1001/jama.2009.1462.PubMed CentralView ArticlePubMed
- Haentjens P, Magaziner J, Colonemeric CS, Vanderscheuren D, Milisin K, Velkeniers B: Excess mortality after hip fracture among older women and men. Ann Intern Med. 2010, 152: 380-390. 10.7326/0003-4819-152-6-201003160-00008.PubMed CentralView ArticlePubMed
- Haleem S, Lutchman L, Mayahi R, Grice JE, Parker MJ: Mortality following hip fracture: trends and geographical variations over the last 40 years. Injury Int J Care Injured. 2008, 39: 1157-1163. 10.1016/j.injury.2008.03.022.View Article
- Richmond J, Aharonoff GB, Zuckerman JD, Koval KJ: Mortality risk after hip fracture. J Orthop Trauma. 2003, 17: 53-56. 10.1097/00005131-200301000-00008.View ArticlePubMed
- Andersen RM: Revisiting the behavioral model and access to medical care: does it matter?. J Health Soc Behav. 1995, 36: 1-10. 10.2307/2137284.View ArticlePubMed
- Roche JJ, Wenn RT, Sahota O, Moran CG: Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: prospective observational cohort study. BMJ. 2005, 331: 1374-1379. 10.1136/bmj.38643.663843.55.PubMed CentralView ArticlePubMed
- Robbins JA, Biggs ML, Cauley J: Adjusted mortality after hip fracture: from the cardiovascular health study. J Am Geriatr Soc. 2006, 54: 1885-1891. 10.1111/j.1532-5415.2006.00985.x.View ArticlePubMed
- Maeng DD, Graham J, Graf TR, Liberman JN: Reducing long-term cost by transforming primary care: evidence from Geisinger’s medical home model. Am J Manag Care. 2012, 18: 149-155.PubMed
- Jencks SF, Williams MV, Coleman EA: Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med. 2009, 360: 1418-1428. 10.1056/NEJMsa0803563.View ArticlePubMed
- California HealthCare Foundation: Uncoordinated Care: A Survey of Physician and Patient Experience. 2007, Oakland, CA: California HealthCare Foundation
- Brown R: A Report Commissioned by the National Coalition on Care Coordination (N3C). The Promise of Care Coordination: Models that Decrease Hospitalizations and Improve Outcomes for Medicare Beneficiaries with Chronic Illnesses. 2009, Princeton, NJ: Mathematica Policy Research, Inc
- Schoen C, Osborn R, How SKH, Doty M, Peugh J: In chronic condition: experiences of patients with complex health care needs, in eight countries. Health Affairs. 2008, 28 (1): w1-16, 2009-
- Shepperd S, McClaren J, Phillips CO: Discharge planning from hospital to home. Cochrane Database Syst Rev. 2010, 1: CD000313-PubMed
- Jack BW, Chetty VK, Anthony D: A reengineered hospital discharge program to decrease rehospitalizations: a randomized trial. Ann Intern Med. 2009, 150: 178-187. 10.7326/0003-4819-150-3-200902030-00007.PubMed CentralView ArticlePubMed
- Menninger B: Reinventing Healthcare Delivery: Innovation and Improvement behind the Scenes. 2009, Oakland, CA: California Healthcare Foundation Issue Brief [serial online]
- Wagner EH, Austin BT, Davis C, Hindmarsh M, Schaefer J, Bonomi AE: Improving chronic illness care: translating evidence into action. Health Aff. 2001, 20: 64-78. 10.1377/hlthaff.20.6.64.View Article
- American College of Physicians (ACP): Joint principles of the patient-centered medical home.http://www.aafp.org/dam/AAFP/documents/practice_management/pcmh/initiatives/PCMHJoint.pdf,
- Gilfillan RJ, Tomcavage J, Rosenthal MB: Value and the Medical Home: Effects of Transformed Primary Care. Am J Manage Care. 2010, 16: 607-614.
- Steele GD, Haynes JA, Davis DE: How Geisinger's advanced medical home model argues the case for rapid-cycle innovation. Health Aff. 2010, 29: 2047-2053. 10.1377/hlthaff.2010.0840.View Article
- Graham J, Tomcavage J, Salek DM, Sciandra J, Davis DE, Stewart WF: Post-discharge monitoring using interactive voice response system reduces 30-day readmission rates in a case-managed Medicare population. Med Care. 2012, 50: 50-57. 10.1097/MLR.0b013e318229433e.View ArticlePubMed
- Szende A, Williams A: Measuring Self-Reported Population Health: An International Perspective Based on EQ-5D. 2004, Rotterdam, NL: EuroQol Group
- Harris WH: Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. JBJS. 1969, 51A: 737-755.
- Rosenbaum PR, Rubin DB: The central role of the propensity score in observational studies for causal effects. Biometrika. 1983, 70: 41-10.1093/biomet/70.1.41.View Article
- D'Agostino RB: Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. Stat Med. 1998, 17: 2265-2281. 10.1002/(SICI)1097-0258(19981015)17:19<2265::AID-SIM918>3.0.CO;2-B.View ArticlePubMed
- Rubin DB: On principles for modeling propensity scores in medical research. Pharmacoepidemiol Drug Saf. 2004, 13: 855-857. 10.1002/pds.968.View ArticlePubMed
- Johnston AT, Barnsdale L, Smith R, Duncan K, Hutchison JD: Changes in long-term mortality associated with fractures of the hip: evidence from the Scottish hip fracture audit. JBJS Br. 2010, 92B: 989-993.
- Butler M, Forte ML, Joglekar SB: Evidence summary: systematic review of surgical treatments for geriatric hip fractures. JBJS. 2011, 93: 1104-1115.View Article
- Rahme E, Kahn SR, Dasgupta K: Short-term mortality associated with failure to receive home care after hemiarthroplasty. CMAJ. 2010, 182: 1421-1426. 10.1503/cmaj.091209.PubMed CentralView ArticlePubMed
- Grigoryan K, Javedan H, Rudoph J: Ortho-geriatric care models and outcomes in hip fracture patients: a systematic review and meta-analysis. J Orthop Trauma. 2013, [Epub ahead of print]
- Friedman S, Mendelson D, Bingham K: Impact of a comanaged geriatric fracture center on short-term hip fracture outcomes. Arch Intern Med. 2009, 169: 1712-1717. 10.1001/archinternmed.2009.321.View ArticlePubMed
- Bhattacharyya R, Agrawal Y, Elphick H: A unique orthogeriatic model: a step forward in improving the quality of care for hip fracture patients. Int J Surg. 2013, 11: 1083-1086. 10.1016/j.ijsu.2013.09.018.View ArticlePubMed
- Gohler A, Januzzi JL, Worrell SS: A systematic meta-analysis of the efficacy and heterogeneity of disease management programs in congestive heart failure. J Card Fail. 2006, 12: 554-567. 10.1016/j.cardfail.2006.03.003.View ArticlePubMed
- Roccaforte R, Demers C, Baldassarre F, Teo KK, Yusuf S: Effectiveness of comprehensive disease management programmes in improving clinical outcomes in heart failure patients. A meta-analysis. Eur J Heart Fail. 2005, 7: 1133-1144. 10.1016/j.ejheart.2005.08.005.View ArticlePubMed
- Whellan DJ, Hasselblad V, Peterson E, O'Connor CM, Schulman KA: Metaanalysis and review of heart failure disease management randomized controlled clinical trials. Am Heart J. 2005, 149: 722-729. 10.1016/j.ahj.2004.09.023.View ArticlePubMed
- Yu DS, Thompson DR, Lee DT: Disease management programmes for older people with heart failure: crucial characteristics which improve post-discharge outcomes. Eur Heart J. 2006, 27: 596-612. 10.1093/eurheartj/ehi656.View ArticlePubMed
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