Table 1 Characteristics of studies and intervention details for rotator cuff calcifying tendinitis
Author year | Design | Setting | TKA/THA | Intervention | Most important Inclusion criteria | Sample size (n) | Intervention vs. Control (n) | Follow-up | Primary endpoint | Secondary endpoints | Patients with fall incident (%) | Mental state altering medications related fall incident (%) | Statistical analysis | NOS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ardeljan, 2021 [23] | Retrospective matched-controlled | Insurance database | TKA | Postop Zolpidem | TKA | 594.973 (374.681 female) | 99.178 (cases) 495.795 (control) | 90 days | Complications including falls | None | 35.521 (5.9%) | Zolpidem user: 6486 (18,3%) No-zolpidem user: 29,035 (81,7%) | Multivariate logistic regression | 7 |
Hill, 2021 [24] | Prospective observational cohort study | Single center | TKA | Postop CNS medications | TKA, > 60 | 251 (140 female) | N/A | 12 months | Fall rate | Injurious falls, multiple falls | 102 (40.6%) | Mental state altering medication-user: 47 (46.1%) No-mental state altering medication user: 55 (53.9%) | Logistic and negative binomial regression | 6 |
Hill, 2021 [22] | Prospective observational cohort study | Single center | THA | Postop mental state altering medications | THA, > 60 | 167 (91 female) | N/A | 12 months | Fall rate | Injurious falls, multiple falls | 67 (40.1%) | Mental state altering medication user: 59 (88.1%) No-mental state altering medication user: 8 (11.9%) | Logistic and negative binomial regression | 6 |
Jörgense, 2013 [21] | Prospective, descriptive, multicenter study | Danish National Patient registry | TKA/THA | Postop pharmacologically treated psychiatric disease | THA/TKA | 5145 (2932 female) | N/A | 90 days | Fall-related hospital admissions after fast-track | Risk factors for falls | 92 (1.8%) | Antipsychotic user: 16 (17.4%) No-antipsychotic user: 76 (82.6%) | Univariate / multivariate logistic regression | 5 |
Levinger, 2017 [20] | Prospective, observational | Single center | TKA/THA | Postop antidepressant | THA/TKA | 243 (128 female) | N/A | 12 months | Falls | Circumstances of falls | 82 (33.7%) | Antidepressant user: 16 (19.5%) No-antidepressant user: 66 (80.5%) | Binary logistic regression | 6 |