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Table 6 Comparison of HFE gene status with complications using Fisher's exact test.

From: The influence of iron status and genetic polymorphisms in the HFE gene on the risk for postoperative complications after bariatric surgery: a prospective cohort study in 1,064 patients

Complications None
N = 910
Any*
N = 154
Any vs. None
p-value
Major*
N = 47
Major vs. None
p-value
Minor*
N = 107
Minor vs. None
p-value
C282Y        
   Normal/Hetero, N (%) 907 (99%) 154 (100%) 0.99 47 (100%) 0.99 107 (0%) 0.99
   Homo, N (%) 3 (<1%) 0 (0%)   0 (0%)   0 (0%)  
H63D        
   Normal/Hetero, N (%) 888 (98%) 146 (95%) 0.065 44 (94%) 0.12 102 (95%) 0.19
   Homo, N (%) 22 (2%) 8 (5%)   3 (6%)   5 (5%)  
C282Y/H63D**        
   Allele dose <2 870 (96%) 141 (92%) 0.043 43 (91%) 0.27 98 (92%) 0.089
   Allele dose 2+ 40 (4%) 13 (8%)   4 (9%)   9 (8%)  
  1. *Complications were limited to those occurring within 30-days of discharge
  2. **An allele dose of 2+ includes all patients that were Homozygous for C282Y, Homozygous for H63D, or Heterozygous for both C282Y and H63D.