The influence of iron status and genetic polymorphisms in the HFE gene on the risk for postoperative complications after bariatric surgery: a prospective cohort study in 1,064 patients

Table 6 Comparison of HFE gene status with complications using Fisher's exact test.

Complications	None N = 910	Any* N = 154	Any vs. None p-value	Major* N = 47	Major vs. None p-value	Minor* N = 107	Minor vs. None p-value
C282Y
Normal/Hetero, N (%)	907 (99%)	154 (100%)	0.99	47 (100%)	0.99	107 (0%)	0.99
Homo, N (%)	3 (<1%)	0 (0%)		0 (0%)		0 (0%)
H63D
Normal/Hetero, N (%)	888 (98%)	146 (95%)	0.065	44 (94%)	0.12	102 (95%)	0.19
Homo, N (%)	22 (2%)	8 (5%)		3 (6%)		5 (5%)
C282Y/H63D**
Allele dose <2	870 (96%)	141 (92%)	0.043	43 (91%)	0.27	98 (92%)	0.089
Allele dose 2+	40 (4%)	13 (8%)		4 (9%)		9 (8%)

*Complications were limited to those occurring within 30-days of discharge
**An allele dose of 2+ includes all patients that were Homozygous for C282Y, Homozygous for H63D, or Heterozygous for both C282Y and H63D.

ISSN: 1754-9493