Table 2 Results of blood tests of Case 2

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Serum Total Protein: 77 g/L; Albumin: 41 g/L.

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Serum protein electrophoresis: No abnormal bands detected.

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Serum immunoglobulins:

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Serum Immunoglobulin G: 18.09 g/L (reference range: 6.0-16.0)

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Serum Immunoglobulin A: 4.14 g/L (reference range: 0.8 – 2.8)

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Serum Immunoglobulin M: 2.08 g/L (reference range: 0.5 – 1.9). Polyclonal increase of immunoglobulins was associated with infection, liver disease, or various connective tissue diseases.

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Serum Connective Tissue Diseases screen: Negative (tested for U1RNP, SS-ARo (60 kDa, 52 kDa), SS-B/La, Centromere B, Scl-70, Jo-1, Fibrillarin, RNA Pol III, Rib-P, PM-Scl, and PCNA, Mi-2 proteins and Sm proteins and dsDNA).

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Serum Glomerular Basement Membrane Screen: Negative. GBM Quantification: less than 0.8 Elisa units (0–6.9).

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Serum Neutrophil Cytoplasmic Antibody Screen by fluorescence: Negative.

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Serum Anti-Proteinase 3 (c-ANCA): Negative 0.2 IU/ml (0–1.9).

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Serum Anti-Myeloperoxidase (p-ANCA): Negative (less than 0.2 (0–3.4).