From: Current preventive measures for health-care associated surgical site infections: a review
Intraoperative interventions | Summary | References |
---|---|---|
Prophylactic antibiotics | • Prophylactic antibiotics are effective in reducing SSI rates | |
• Discontinue within 24 hours of closure to prevent superinfection | ||
• Redosing may be beneficial for procedures > 4 hours or if EBL > 1.5 L | ||
• Timing, duration, selection of antibiotics should be incorporated into the "time-out" to improve compliance | ||
Skin preparation | • No clear evidence that one preparation solution is superior | |
Wound irrigation | • Important to remove loose, necrotic tissue, debris, and microorganisms from surgical site | |
• No difference in infection rates between saline and tap water | ||
• Dilute betadine solution may be of benefit | ||
Thermoregulation | • Maintaining perioperative normothermia may reduce SSI rates | |
Antiseptic-coated sutures | • Effective in reducing SSI rates in neurosurgical patients, but cost-effectiveness has yet to be determined | |
Operating room traffic | • Limit OR traffic flow | [74] |