61 years old male, who had right calcaneus fracture with depression of the intra articular joint. A, B the injury radiograph and Sagittal CT showing the injury with severe comminution and depression. Two days after the injury, patient had open reduction using sinus tarsi approach with internal fixation using two cannulated 6.5 mm screws from the inferior aspect of the calcaneus tuberosity and three cortical screws supporting the depressed subtalar fragment. Synthetic bone grafting by Calcium Phosphate was used to fill the gap after elevating the depression. C, D and E: post operative radiograph, sagittal and coronal CT showing the reduction, fixation and grafting of the fracture. At the three weeks follow up, the patient presented with wound dehiscence and infection. Surgical debridement was performed and negative pressure wound therapy was applied until the wound healed with secondary intention to allow for regeneration of the deep defect. F: shows wound dehiscence under treatment by negative pressure wound therapy.