The grass is not always greener: a multi-institutional pilot study of marijuana use and acute pain management following traumatic injury

Table 2 Mean (standard error) daily opioid consumption and daily pain numeric rating scale (NRS) scores, by marijuana status and other drug use

Outcome, stratified	Marijuana user (n = 54)	No marijuana use (n = 207)	p value
No other drug use^a	(n = 40)	(n = 198)
Mean opioid consumption	8.53 (0.33)	5.86 (0.18)	< 0.001
LSM^b opioid consumption	7.57 (0.36)	5.65 (0.18)	< 0.001
Mean pain NRS score	5.17 (0.15)	4.17 (0.07)	< 0.001
LSM^b mean pain NRS score	4.92 (0.16)	4.19 (0.11)	< 0.001
Other drug use^a	(n = 14)	(n = 9)
Mean opioid consumption	8.81 (0.82)	10.58 (0.97)	0.29
LSM^b opioid consumption	5.59 (0.81)	6.10 (1.17)	0.71
Mean pain NRS score	5.02 (0.24)	5.54 (0.25)	0.15
LSM^b mean pain NRS score	5.28 (0.34)	6.00 (0.48)	0.07

Analyzed with a repeated measures linear mixed model
LSM least square mean
^aDrug use: amphetamines, barbiturates, benzodiazepines, cocaine, methamphetamine, and opiates
^bAdjusted for ISS, age, and cause of motor vehicle crash injury
P < 0.05 in italic is clinically significant

ISSN: 1754-9493