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Table 3 Association of patient factors with bleeding events

From: Safety and efficacy of a new thromboprophylaxis regiment for total knee and total hip replacement: a retrospective cohort study in 265 patients

n (%)a

Any bleed

(n = 43)

No bleed

(n = 222)

p

Female sex

28 (65.1)

140 (63.1)

0.798

Age (mean)

69.1

67.2

0.279

Renal failure

1 (2.3)

4 (1.8)

0.590

Hepatic failure

0 (0.0)

3 (1.4)

1.000

Diabetes

6 (14.0)

23 (10.4)

0.436

Ischaemic Heart Disease

0 (0.0)

16 (7.2)

0.083

Asthma and COPD

10 (23.3)

28 (12.6)

0.068

Hypertension

23 (53.5)

90 (40.5)

0.116

Atrial Fibrillation

3 (7.0)

6 (2.7)

0.165

Previous VTE

2 (4.7)

3 (1.4)

0.187

Vascular disease

0 (0.0)

4 (1.8)

1.000

Partial joint replacement

1 (2.3)

7 (3.2)

1.000

Hip replacement

19 (44.2)

132 (59.4)

0.064

Primary replacement

38 (88.3)

214 (96.4)

0.042

ACE inhibitor/ARB

15 (34.9)

62 (27.9)

0.358

Statin

11 (25.6)

75 (33.8)

0.293

Gastric Protection

16 (37.2)

75 (33.8)

0.665

CCB

10 (23.3)

51 (23.0)

0.968

Aspirin

1 (2.3)

11 (5.0)

0.697

Clopidogrel

1 (2.3)

2 (0.9)

0.413

Ticagrelor

0 (0.0)

0 (0.0)

Dihydropyridine

0 (0.0)

0 (0.0)

Diuretic

9 (20.9)

28 (12.6)

0.150

Antiretroviral

1 (2.3)

2 (0.9)

0.413

Warfarin

0 (0.0)

0 (0.0)

Length of operation (mean)b

2.16

2.02

0.188

  1. aUnless specified otherwise
  2. bDocumentation only available for 255 patients (43 patients experienced any bleeding event and 212 patients did not experience any bleeding event)
  3. ACEi – Angiotensin converting enzyme inhibitor; ARB – Aldosterone receptor blocker; CCB – Calcium channel blocker; COPD – chronic obstructive pulmonary disease