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Table 3 Potential perioperative risk factors and PPCS, Mechanical Ventilation and 30-day mortality

From: Root causes and outcomes of postoperative pulmonary complications after abdominal surgery: a retrospective observational cohort study

Variable

n

PPC

(Postoperative Pulmonary Complications)

Mechanical Ventilation

30-Day Mortality

≤ 48 h

> 48 h

OR (95% C.I.)a

OR (95% C.I.)a

OR (95% C.I.)a

OR (95% C.I.)a

Sex

 M

45

1

1

1

1

 F

15

0.48 (0.15–1.58)

3.50 (0.87–14.11)

0.59 (0.15–2.35)

2.31 (0.62–8.64)

NMBD

 No

43

1

1

1

1

 Yes

17

18.40 (2.24–151.35)

0.67 (0.21–2.08)

**

2.81 (0.78–10.12)

Age

60

1.05 (0.98–1.13)

0.95 (0.89–1.03)

1.01 (0.93–1.10)

1.05 (0.97–1.15)

ASA

 1

18

1

1

1

1

 2

17

0.37 (0.07–1.80)

0.56 (0.14–2.21)

0.94 (0.05–16.35)

1.09 (0.27–4.41)

 3

13

0.32 (0.06–1.70)

0.31 (0.07–1.38)

0.13 (0.01–1.37)

0.17 (0.02–1.60)

 4

12

0.04 (0.01–0.28)

2.50 (0.41–15.23)

0.06 (0.01–0.59)

**

ARISCAT

 Low risk < 26

14

1

1

1

1

 Intermediate Risk 26–44

16

1.65 (0.37–7.37)

0.21 (0.04–1.29)

0.72 (0.10–5.09)

1.50 (0.32–6.99)

 High risk > 45

30

0.98 (0.27–3.53)

0.17 (0.03–0.88)

0.55 (0.10–3.06)

0.28 (0.05–1.47)

Respiratory Infection

 No

50

1

1

1

1

 Yes

10

1.00 (0.25–4.00)

1.69 (0.39–7.31)

2.54 (0.29–22.27)

1.71 (0.38–7.84)

Anemia

 No

30

1

1

1

1

 Yes

30

0.76 (0.27–2.13)

2.33 (0.81–6.73)

1.00 (0.28–3.54)

1.22 (0.36–4.17)

Incision Type

 Bilateral subcostal

21

1

1

1

1

 Median

39

0.22 (0.06–0.79)

4.14 (1.34–12.72)

0.13 (0.02–1.07)

0.55 (0.16–1.91)

LPT vs. LPC

 LPC (Laparoscopy)

19

1

1

1

1

 LPT (Laparotomy)

41

1.14 (0.38–3.43)

1.14 (0.38–3.43)

1.73 (0.47–6.40)

0.45 (0.13–1.58)

Surgery Duration

     

  < 180 min

42

1

1

1

1

  > 180 min

18

3.18 (0.90–11.28)

0.29 (0.09–0.90)

2.50 (0.49–12.79)

2.50 (0.70–8.92)

Smokers

 No

35

1

1

1

1

 Yes

25

1.33 (0.46–3.83)

0.75 (0.26–2.14)

1.00 (0.28–3.61)

0.55 (0.15–2.04)

BMI

  < 18

12

1

1

1

1

 18–25

20

0.78 (0.15–3.93)

1.40 (0.33–5.93)

**

0.75 (0.14–4.13)

 25–30

16

0.56 (0.11–2.90)

2.33 (0.51–10.78)

**

1.36 (0.25–7.32)

30–35

12

0.11 (0.02–0.71)

15.40 (1.47–160.97)

**

0.27 (0.02–3.09)

COPD/Asthma History

 No

42

1

1

1

1

 Yes

18

0.56 (0.18–1.70)

2.15 (0.65–7.11)

0.21 (0.06–0.80)

1.63 (0.45–5.92)

POSA

  ≤ 35 g/L

8

5.55 (0.64–48.41)

0.63 (0.14–2.79)

1.88 (0.21–16.92)

19.29 (3.23–115.22)

  > 35 g/l

52

1

1

1

1

Lactate

  < 4 mmol/l

14

1

1

1

1

  > 4 mmol/l

46

0.52 (0.14–1.90)

1.17 (0.35–3.92)

**

0.38 (0.10–1.44)

PREOP Abnormal Arterial blood gases

 No

20

1

1

1

1

 Yes

40

3.50 (1.14–10.74)

0.16 (0.04–0.63)

1.57 (0.43–5.77)

0.49 (0.14–1.74)

Pa02 ≤ 50 ≥ 60 Moderate - Severe ARF

 No

25

1

1

1

1

 Yes

35

2.36 (0.82–6.83)

0.41 (0.14–1.23)

1.53 (0.43–5.44)

1.82 (0.49–6.74)

Pa02/FiO2

  < 100

21

0.83 (0.28–2.45)

1.13 (0.38–3.35)

1.80 (0.43–7.53)

**

 101–300

39

1

1

1

1

PREOP Abnormal Chest radiography

 No

36

1

1

1

1

 Yes

24

3.00 (0.97–9.30)

0.37 (0.13–1.09)

4.23 (0.84–21.40)

2.06 (0.59–7.13)

  1. ASA PS American Society of Anesthesiologists physical status, BMI body mass index, COPD Chronic Obstructive Pulmonary Disease, FiO2 Inspiratory oxygen fraction, LPC Laparoscopy, LPT Laparotomy, NMBD Neuromuscular blocking drugs, PaO2 arterial oxygen pressure, PREOP preoperative period, POSA preoperative serum albumin. a Unadjusted (Univariable Model);** No cases in at least one of the groups; Bold - significant values.