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Table 4 Bivariate and multivariable linear regression models of the highest pain score in the first 48 h post-op

From: Risk factors for liposomal bupivacaine resistance after total hip or knee arthroplasties: a retrospective observational cohort in 237 patients

 Highest Pain Score (0-48 h)
BivariateMultivariable
AD (95%CI)p-valueAD (95% CI)p-value
Gender
 Male0
 Female0.29 (−0.32, 0.91)0.35
Age-0.05 (− 0.07, − 0.02)0.0002-0.05 (− 0.07, − 0.02)0.001
BMI0.03 (0.01, 0.05)0.020.01 (− 0.01, 0.04)0.28
Side
 Right0
 Left0.22 (− 0.36, 0.80)0.45
Surgery
 Primary Total Knee00
 Revision Total Knee−0.82 (−1.89, 0.25)0.13−0.87 (− 1.92, 0.18)0.12
 Primary Total Hip−0.83 (−1.48, − 0.19)0.01− 1.03 (− 1.68, − 0.38)0.002
 Revision Total Hip−0.01 (− 1.17, 1.15)0.99− 0.23 (− 1.43, 0.98)0.71
 Bilateral Knee2.12 (− 0.89, 5.14)0.172.27 (− 0.56, 5.11)0.12
PCA
 Yes0.70 (0.01, 1.39)0.050.40 (−0.32, 1.12)0.28
 No00
Type of Block
 None0
 Spinal/Epidural0.69 (−0.20, 1.59)0.13
 Femoral/Intraarticular0.94 (−0.39, 2.27)0.17
Smoker
 Yes0.39 (−0.32, 1.10)0.28
 No0
Alcohol
 Yes0.28 (−0.46, 1.01)0.46
 No0
Hx Pain Management
 Yes0.69 (0.12, 1.27)0.020.82 (−3.30, 4.94)0.70
 No00
Home Pain Meds
 None00
 Opioids0.97 (0.34, 1.59)0.0020.09 (−4.06, 4.24)0.97
 Neurontin/Lyrica0.52 (−0.93, 2.00)0.49−0.62 (− 4.98, 3.74)0.78
 Other−0.38 (−1.46, 0.71)0.49−1.07 (−5.08, 2.94)0.60
Steroids
 Yes0.23 (−0.76, 1.22)0.65
 No0
Antidepressants
 Yes0.50 (−0.45, 1.44)0.30
 No0
Diabetes
 Yes−0.02 (−0.65, 0.61)0.94
 No0
  1. Ref = 0