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Table 2 Prophylactic Antibiotics Protocol

From: Adherence to a standardized infection reduction bundle decreases surgical site infections after colon surgery: a retrospective cohort study on 526 patients

Prophylactic Antibiotics
Cefazolin 2 gm (3 gm if > 120kg) and Metronidazole 1000 mg IV
- With Penicillin allergy: Ciprofloxacin 400 mg and Metronidazole 1000 mg IV
Intraoperative Antibiotic Redosing
Cefazolin every 4 hours
Metronidazole if case > 8 hours
- Dosing should be adjusted based on renal function. Cefazolin is renally eliminated
- Prophylactic antibiotics are stopped at 24 hours