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Table 6 Effect of TXA and other variables on total blood loss, 24-hour drain output, postoperative length of stay, and transfusion rate adjusted for other covariates. THA

From: Tranexamic acid lowers transfusion requirements and hospital length of stay following revision total hip or knee arthroplasty

Variable

Regression Coefficient (Unadjusted)

p

Regression Coefficient (Adjusted)

p

Total blood loss

TXA

-130.9

0.012

-98.4

0.143

Age

5.9

0.007

6.2

0.059

BMI

6.8

0.054

6.7

0.162

ASA Class

2.2

0.939

1.9

0.963

Preop Hb

-29.9

0.062

-11.2

0.606

Female sex

-38.5

0.488

-104.1

0.173

24h drain output

TXA

-48.4

0.507

-2.2

0.978

Age

2.4

0.457

5.1

0.182

BMI

6.1

0.364

0.7

0.923

ASA Class

59.4

0.091

73.1

0.118

Preop Hb

20.0

0.401

31.1

0.222

Female sex

-155.4*

0.033

-116.7

0.194

Postoperative length of stay

TXA

-2.38

<0.001

-1.68

0.032

Age

0.07

0.016

0.01

0.750

BMI

0.15

0.009

0.16

0.005

ASA Class

0.04

0.927

0.02

0.971

Preop Hb

-0.31

0.173

-0.41

0.105

Female sex

-1.02

0.175

-0.63

0.460

Postoperative units transfused

TXA

-0.84

0.103

-0.23

0.615

Age

0.08

<0.001

0.07

0.004

BMI

0.02

0.601

0.02

0.595

ASA Class

0.64

0.016

0.57

0.054

Preop Hb

-0.44

0.006

-0.22

0.155

Female sex

-0.28

0.614

-0.38

0.469