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Table 4 Incidence proportion of acute myocardial infarction in patients undergoing elective spinal fusion during selected risk windows, crude and stratified by selected characteristics

From: The incidence of acute myocardial infarction after elective spinal fusions or joint replacement surgery in the United States: a large-scale retrospective observational cohort study in 322,585 patients

 

During initial hospitalization

Up to 30 days post-operation

Up to 90 days post-operation

Up to 180 days post-operation

Up to 365 days post-operation

Number of patients at risk

Number of cases

Incidence proportion (95% confidence interval)

Number of patients at risk

Number of cases

Incidence proportion (95% confidence interval)

Number of patients at risk

Number of cases

Incidence proportion (95% confidence interval)

Number of patients at risk

Number of cases

Incidence proportion (95% confidence interval)

Number of patients at risk

Number of cases

Incidence proportion (95% confidence interval)

Crude

67,020

241

0.36% (0.31%, 0.41%)

67,025

324

0.48% (0.43%, 0.54%)

67,028

417

0.62% (0.56%, 0.68%)

67,033

530

0.79% (0.72%, 0.86%)

67,034

702

1.05% (0.97%, 1.12%)

Stratifications by:

Age

   ≥ 18–55

26,702

27

0.10% (0.06%, 0.14%)

26,702

38

0.14% (0.10%, 0.19%)

26,703

52

0.20% (0.14%, 0.25%)

26,706

73

0.27% (0.21%, 0.34%)

26,707

108

0.40% (0.33%, 0.48%)

  56–65

18,449

58

0.31% (0.23%, 0.40%)

18,450

80

0.43% (0.34%, 0.53%)

18,451

113

0.61% (0.50%, 0.73%)

18,452

148

0.80% (0.67%, 0.93%)

18,452

201

1.09% (0.94%, 1.24%)

  66–75

15,924

96

0.60% (0.48%, 0.72%)

15,924

126

0.79% (0.65%, 0.93%)

15,925

154

0.97% (0.82%, 1.12%)

15,925

193

1.21% (1.04%, 1.38%)

15,925

247

1.55% (1.36%, 1.74%)

  76–< 86

5,945

60

1.00% (0.76%, 1.26%)

5,949

80

1.35% (1.05%, 1.64%)

5,949

98

1.65% (1.32%, 1.97%)

5,950

116

1.95% (1.60%, 2.30%)

5,950

146

2.45% (2.06%, 2.85%)

Sex

  Male

38,149

171

0.45% (0.38%, 0.52%)

38,151

219

0.57% (0.50%, 0.65%)

38,153

285

0.75% (0.66%, 0.83%)

38,156

359

0.94% (0.84%, 1.04%)

38,157

482

1.26% (1.15%, 1.38%)

  Female

28,848

70

0.24% (0.19%, 0.30%)

28,851

105

0.36% (0.30%, 0.43%)

28,852

132

0.46% (0.38%, 0.54%)

28,854

171

0.59% (0.50%, 0.68%)

28,854

219

0.76% (0.66%, 0.86%)

  Unknown

23

0

0.00% (0.00%, 0.00%)

23

0

0.00% (0.00%, 0.00%)

23

0

0.00% (0.00%, 0.00%)

23

0

0.00% (0.00%, 0.00%)

23

1

4.35% (0.11%, 21.95%)

Race

  White

59,479

212

0.36% (0.31%, 0.40%)

59,482

288

0.48% (0.43%, 0.54%)

59,483

371

0.62% (0.56%, 0.69%)

59,487

478

0.80% (0.73%, 0.88%)

59,488

637

1.07% (0.99%, 1.15%)

  Black or African American

4,399

18

0.41% (0.22%, 0.60%)

4,399

20

0.46% (0.26%, 0.65%)

4,401

27

0.61% (0.38%, 0.84%)

4,402

33

0.75% (0.50%, 1.01%)

4,402

43

0.98% (0.69%, 1.27%)

  Asian

356

4

1.11% (0.31%, 2.85%)

356

5

1.41% (0.46%, 3.25%)

356

5

1.40% (0.46%, 3.25%)

356

5

1.41% (0.46%, 3.25%)

356

5

1.41% (0.46%, 3.25%)

  Other/Unknown

2,786

7

0.25% (0.07%, 0.44%)

2,788

11

0.50% (0.24%, 0.77%)

2,788

14

0.50% (0.27%, 0.77%)

2,788

14

0.50% (0.24%, 0.77%)

2,788

17

0.61% (0.32%, 0.90%)

Type 1 Diabetes during baseline

  Yes

480

6

1.25% (0.26%, 2.24%)

480

7

1.46% (0.39%, 2.53%)

480

9

1.88% (0.66%, 3.09%)

480

13

2.71% (1.26%, 4.16%)

480

18

3.75% (2.05%, 5.45%)

  No

66,540

235

0.35% (0.31%, 0.40%)

66,545

317

0.48% (0.42%, 0.53%)

66,548

408

0.61% (0.55%, 0.67%)

66,553

517

0.78% (0.71%, 0.84%)

66,554

684

1.03% (0.95%, 1.11%)

Type 2 Diabetes during baseline

  Yes

9,204

65

0.71% (0.54%, 0.88%)

9,209

96

1.04% (0.84%, 1.25%)

9,210

127

1.38% (1.14%, 1.62%)

9,210

162

1.76% (1.49%, 2.03%)

9,210

213

2.31% (2.00%, 2.62%)

  No

57,816

176

0.30% (0.26%, 0.35%)

57,816

228

0.39% (0.34%, 0.45%)

57,818

290

0.50% (0.44%, 0.56%)

57,823

368

0.64% (0.57%, 0.70%)

57,824

489

0.85% (0.77%, 0.92%)

Revisional surgery on the same day as index surgery

  Yes

534

3

0.56% (0.12%, 1.63%)

534

4

0.75% (0.21%, 1.91%)

534

4

0.75% (0.21%, 1.91%)

534

4

0.75% (0.21%, 1.91%)

534

6

1.12% (0.23%, 2.02%)

  No

66,486

238

0.36% (0.31%, 0.40%)

66,491

320

0.48% (0.43%, 0.54%)

66,494

413

0.62% (0.56%, 0.68%)

66,499

526

0.79% (0.72%, 0.86%)

66,500

696

1.05% (0.97%, 1.12%)

Total length of hospital stay

  1–5 days

59,512

108

0.18% (0.15%, 0.22%)

59,516

174

0.29% (0.25%, 0.34%)

59,518

244

0.41% (0.36%, 0.46%)

59,522

341

0.57% (0.51%, 0.63%)

59,523

488

0.82% (0.75%, 0.89%)

  6–10 days

5,715

67

1.17% (0.90%, 1.45%)

5,716

82

1.43% (1.13%, 1.74%)

5,717

196

1.68% (1.35%, 2.01%)

5,717

110

1.92% (1.57%, 2.28%)

5,717

124

2.17% (1.79%, 2.55%)

   > 10 days

1,793

66

3.68% (2.81%, 4.55%)

1,793

68

3.79% (2.91%, 4.68%)

1,793

77

4.29% (3.36%, 5.23%)

1,794

79

4.40% (3.45%, 5.35%)

1,794

90

5.02% (4.00%, 6.03%)

Use of implanted material during surgery on the same day as index surgery

  Yes

3,799

13

0.34% (0.16%, 0.53%)

3,799

19

0.50% (0.28%, 0.73%)

3,799

22

0.58% (0.34%, 0.82%)

3,799

26

0.68% (0.42%, 0.95%)

3,799

34

0.90% (0.60%, 1.20%)

  No

63,221

228

0.36% (0.31%, 0.41%)

63,226

305

0.48% (0.43%, 0.54%)

63,229

395

0.62% (0.57%, 0.69%)

63,234

504

0.80% (0.73%, 0.87%)

63,235

668

1.06% (0.98%, 1.14%)

Medical history of acute myocardial infarction

  Yes

415

53

12.77% (9.56%, 15.98%)

416

66

15.87% (12.35%, 19.38%)

416

81

19.47% (15.67%, 23.28%)

416

93

22.36% (18.35%, 26.36%)

416

115

27.64% (23.25%, 31.94%)

  No

66,605

188

0.28% (0.24%, 0.32%)

66,609

258

0.39% (0.34%, 0.44%)

66,612

336

0.50% (0.45%, 0.56%)

66,617

437

0.66% (0.60%, 0.72%)

66,618

587

0.88% (0.81%, 0.95%)