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Table 6 Incidence proportion of acute myocardial infarction in patients undergoing elective total knee arthroplasty during selected risk windows, crude and stratified by selected characteristics

From: The incidence of acute myocardial infarction after elective spinal fusions or joint replacement surgery in the United States: a large-scale retrospective observational cohort study in 322,585 patients

 

During initial hospitalization

Up to 30 days post-operation

Up to 90 days post-operation

Up to 180 days post-operation

Up to 365 days post-operation

Number of patients at risk

Number of cases

Incidence proportion (95% confidence interval)

Number of patients at risk

Number of cases

Incidence proportion (95% confidence interval)

Number of patients at risk

Number of cases

Incidence proportion (95% confidence interval)

Number of patients at risk

Number of cases

Incidence proportion (95% confidence interval)

Number of patients at risk

Number of cases

Incidence proportion (95% confidence interval)

Crude

165,863

406

0.24% (0.22%, 0.27%)

165,866

557

0.34% (0.31%, 0.36%)

165,866

717

0.43% (0.40%, 0.46%)

165,871

931

0.56% (0.53%, 0.60%)

165,879

1,407

0.85% (0.80%, 0.89%)

Stratifications by:

Age

   ≥ 18–55

23,770

16

0.07% (0.03%, 0.10%)

23,770

30

0.13% (0.08%, 0.17%)

23,770

40

0.17% (0.12%, 0.22%)

23,770

56

0.24% (0.17%, 0.30%)

23,770

88

0.37% (0.29%, 0.45%)

  56–65

56,427

89

0.16% (0.13%, 0.19%)

56,427

132

0.23% (0.19%, 0.27%)

56,427

176

0.31% (0.27%, 0.36%)

56,427

229

0.41% (0.35%, 0.46%)

56,429

348

0.62% (0.55%, 0.68%)

  66–75

57,710

155

0.27% (0.23%, 0.31%)

57,711

204

0.35% (0.31%, 0.40%)

57,711

259

0.45% (0.39%, 0.50%)

57,713

347

0.60% (0.54%, 0.66%)

57,716

522

0.90% (0.83%, 0.98%)

  76–< 86

27,956

146

0.52% (0.44%, 0.61%)

27,958

191

0.68% (0.59%, 0.78%)

27,958

242

0.87% (0.76%, 0.97%)

27,961

299

1.07% (0.95%, 1.19%)

27,964

449

1.61% (1.46%, 1.75%)

Sex

  Male

66,721

230

0.34% (0.30%, 0.39%)

66,722

326

0.49% (0.44%, 0.54%)

66,722

422

0.63% (0.57%, 0.69%)

66,723

540

0.81% (0.74%, 0.88%)

66,727

825

1.24% (1.15%, 1.32%)

  Female

99,087

176

0.18% (0.15%, 0.20%)

99,089

231

0.23% (0.20%, 0.26%)

99,089

295

0.30% (0.26%, 0.33%)

99,093

391

0.39% (0.36%, 0.43%)

99,097

582

0.59% (0.54%, 0.64%)

  Unknown

55

0

0.00% (0.00%, 0.00%)

55

0

0.00% (0.00%, 0.00%)

55

0

0.00% (0.00%, 0.00%)

55

0

0.00% (0.00%, 0.00%)

55

0

0.00% (0.00%, 0.00%)

Race

  White

146,645

354

0.24% (0.22%, 0.27%)

146,647

488

0.33% (0.30%, 0.36%)

146,647

631

0.43% (0.40%, 0.46%)

146,651

826

0.56% (0.52%, 0.60%)

146,658

1,259

0.86% (0.81%, 0.91%)

  Black or African American

11,417

32

0.28% (0.18%, 0.38%)

11,418

42

0.37% (0.26%, 0.48%)

11,418

51

0.45% (0.32%, 0.57%)

11,419

62

0.54% (0.41%, 0.68%)

11,419

94

0.82% (0.66%, 0.99%)

  Asian

1,073

3

0.28% (0.06%, 0.81%)

1,073

4

0.37% (0.10%, 0.95%)

1,073

4

0.37% (0.10%, 0.95%)

1,073

4

0.37% (0.10%, 0.95%)

1,073

5

0.47% (0.15%, 1.08%)

  Other/Unknown

6,728

17

0.25% (0.13%, 0.37%)

6,728

23

0.34% (0.20%, 0.48%)

6,728

31

0.46% (0.30%, 0.62%)

6,728

39

0.58% (0.40%, 0.76%)

6,729

49

0.73% (0.53%, 0.93%)

Type 1 Diabetes during baseline

  Yes

754

4

0.53% (0.14%, 1.35%)

754

9

1.19% (0.42%, 1.97%)

754

10

1.33% (0.65%, 2.14%)

754

11

1.46% (0.60%, 2.31%)

754

15

1.99% (0.99%, 2.99%)

  No

165,109

402

0.24% (0.22%, 0.27%)

165,112

548

0.33% (0.30%, 0.36%)

165,112

707

0.43% (0.40%, 0.46%)

165,117

920

0.56% (0.52%, 0.59%)

165,125

1,392

0.84% (0.80%, 0.89%)

Type 2 Diabetes during baseline

  Yes

26,598

108

0.41% (0.33%, 0.48%)

26,599

158

0.59% (0.50%, 0.69%)

26,599

201

0.76% (0.65%, 0.86%)

26,601

264

0.99% (0.87%, 1.11%)

26,602

372

1.40% (1.26%, 1.54%)

  No

139,265

298

0.21% (0.19%, 0.24%)

139,267

399

0.29% (0.26%, 0.31%)

139,267

516

0.37% (0.34%, 0.40%)

139,270

667

0.48% (0.44%, 0.52%)

139,277

1,035

0.74% (0.70%, 0.79%)

Revisional surgery on the same day as index surgery

  Yes

62,541

142

0.23% (0.19%, 0.26%)

62,543

189

0.30% (0.26%, 0.35%)

62,543

242

0.39% (0.34%, 0.44%)

62,543

315

0.50% (0.45%, 0.56%)

62,545

453

0.72% (0.66%, 0.79%)

  No

103,322

264

0.26% (0.23%, 0.29%)

103,323

368

0.36% (0.32%, 0.39%)

103,323

475

0.46% (0.42%, 0.50%)

103,328

616

0.60% (0.55%, 0.64%)

103,334

954

0.92% (0.86%, 0.98%)

Total length of hospital stay

  1–5 days

158,267

238

0.15% (0.13%, 0.17%)

158,270

379

0.24% (0.22%, 0.26%)

158,270

529

0.33% (0.30%, 0.36%)

158,273

730

0.46% (0.43%, 0.49%)

158,281

1,164

0.74% (0.69%, 0.78%)

  6–10 days

5,458

100

1.83% (1.48%, 2.19%)

5,458

109

2.00% (1.63%, 2.37%)

5,458

113

2.07% (1.69%, 2.45%)

5,458

120

2.20% (1.81%, 2.59%)

5,458

150

2.75% (2.31%, 3.18%)

   > 10 days

2,138

68

3.18% (2.44%, 3.92%)

2,138

69

3.23% (2.48%, 3.98%)

2,138

75

3.51% (2.73%, 4.29%)

2,140

81

3.79% (2.98%, 4.59%)

2,140

93

3.48% (3.48%, 5.21%)

Use of implanted material during surgery on the same day as index surgery

  Yes

1,768

1

0.06% (0.00%, 0.31%)

1,768

4

0.23% (0.06%, 0.58%)

1,768

6

0.34% (0.07%, 0.61%)

1,768

10

0.57% (0.22%, 0.92%)

1,768

15

0.85% (0.42%, 1.28%)

  No

164,095

405

0.25% (0.22%, 0.27%)

164,098

553

0.34% (0.31%, 0.37%)

164,098

711

0.43% (0.40%, 0.47%)

164,103

921

0.56% (0.53%, 0.60%)

164,111

1,392

0.85% (0.80%, 0.89%)

Medical history of acute myocardial infarction

  Yes

864

93

10.76% (8.70%, 12.83%)

864

101

11.69% (9.55%, 13.83%)

864

119

13.77% (11.48%, 16.07%)

864

153

17.71% (15.16%, 20.25%)

864

185

21.41% (18.68%, 24.15%)

  No

164,999

313

0.19% (0.17%, 0.21%)

165,002

456

0.28% (0.25%, 0.30%)

165,002

598

0.36% (0.33%, 0.39%)

165,007

778

0.47% (0.44%, 0.51%)

165,015

1,222

0.74% (0.70%, 0.78%)