Table 2 Triggers used in the study grouped by modules

Care module

1. Transfusion of blood or blood derivatives

2. Cardiorespiratory arrest code

3. Acute dialysis

4. Positive blood culture

5. Radiological test for the study of thrombosis (Unscheduled echo-Doppler during admission, CT angiography)

6. Sudden decrease in hemoglobin equal or greater than 25%.

7. Patient fall

8. Bedsores

9. Patient detention measures

10. Readmission 30 days post-discharge

11. Unscheduled radiology during admission

12. Infection associated with healthcare

Medication module

1. Positive culture for Clostridium difficile antihistamine

2. Partial Thromboplastin Time (PTT) over 100 s

3. INR (International Normalized Ratio) over 6

4. Glycemia under 50 mg/dL

5. Increased serum creatinine x 2 compared to basal level

6. Administration of vitamin K

7. Administration of Flumazenil

8. Administration of Naloxone.

9. Administration of Epinephrine.

10. Administration of anti-emetics

11. Sudden stoppage of the medication

Surgical module

1. Reintervention in the 30 days post-discharge.

2. Unscheduled change in procedure or complication of this.

3. Unscheduled transfer to critical care unit (higher level of care)

4. Unscheduled intubation or repeat intubation

5. Intra-operative radiology

6. Mechanical ventilation greater than 24 hours

7. Intra-operative administration of Flumazenil, Naloxone or Epinephrine.

8. Postoperative increase in troponin greater than 1.5 nanograms/mL

9. Unscheduled injury or removal of an organ

Added based on prior literature and studies

1. Care in the emergency department 30 days post-discharge

2. Unscheduled invasive procedures during admission (interventional radiology, endoscopy)

3. Pathological anatomy unrelated to diagnosis

4. Use of broad spectrum antibiotherapy

5. Use of Total Parenteral Nutrition.

6. Prolonged stay in resuscitation after surgery (over 24 hours).