| VKA users N = 319 | DOAC users N = 229 | P-value | ||
---|---|---|---|---|---|
Preoperative (%) | |||||
 Administration of vitamin K | 28 | (9%) | - | - |  |
 Administration of coagulations factors | 1 | (0%) | - | - |  |
Non-reporting of anticoagulation management as decided by pbysician | 15 | (5%) | 4 | (2%) | 0.06 |
Non-reporting of exact timing of interruption as executed by patient | 174 | (55%) | 92 | (40%) |  < 0.001 |
Conflicting information about perioperative anticoagulant management in medical records | 106 | (33%) | 46 | (20%) |  < 0.001 |
Perioperative (%) | |||||
 Mean blood loss during surgery (SD) | 252 | (227) | 210 | (145) | 0.041 |
 > 500 ml unexpected blood loss during surgery | 12 | (4%) | 2 | (1%) | 0.106 |
Postoperative untill six weeks after surgery | |||||
 Coagulation-related complications, total | 37 | (12%) | 22 | (10%) | 0.10 |
 Tromboembolic complications | 2 | (1%) | 6 | (3%) | 0.06 |
Bleeding complications | 37 | (12%) | 20 | (9%) | 0.30 |
 Clinical relevant non-major bleeding | 29 | (9%) | 18 | (8%) | 0.61 |
 Major bleeding | 8 | (3%) | 2 | (1%) | 0.16 |
Administration of blood transfusion | 24 | (8%) | 6 | (2%) | 0.013 |