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Table 5 “Early 2020” logistic regression covariates pertinent to patient demographics, comorbidities, and selected pulmonary and renal organ management modalities. A P-value < 0.05 was considered statistically significant. Abbreviations: BiPAP, bilevel positive airway pressure; BMI, body mass index; CRRT, continuous renal replacement therapy; ECMO, extracorporeal membrane oxygenation; O2, oxygen

From: Investigational medications in 9,638 hospitalized patients with severe COVID-19: lessons from the “fail-and-learn” strategy during the first two waves of the pandemic in 2020

 

Odds Ratio

95% Confidence Interval

P-Value

Age

1.07

1.06

1.08

< 0.01

Elixhauser Comorbidity Index

1.12

1.07

1.17

< 0.01

Asian vs. white ethnicity

0.41

0.24

0.68

< 0.01

Black vs. white ethnicity

0.54

0.41

0.71

< 0.01

Hispanic vs. white ethnicity

0.66

0.07

6.72

0.76

Multiracial vs. white ethnicity

0.64

0.51

0.81

< 0.01

Native American vs. white ethnicity

1.18

0.25

5.67

0.68

BMI

0.99

0.97

1.00

0.13

Coagulopathy

1.49

1.18

1.87

< 0.01

Dementia

1.48

1.10

2.00

< 0.01

Psychosis

0.74

0.48

1.15

0.14

Cancer

1.67

1.09

2.56

0.04

Surgical procedure

0.39

0.27

0.58

< 0.01

Any O2 administration

4.67

2.32

9.38

< 0.01

Nasal O2 cannula

0.17

0.12

0.25

< 0.01

BiPAP

2.57

2.09

3.16

< 0.01

Invasive ventilation

8.34

6.75

10.3

< 0.01

CRRT

3.65

2.64

5.06

< 0.01

ECMO

3.16

1.21

8.24

0.02