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Fig. 1 | Patient Safety in Surgery

Fig. 1

From: Induction of immune gene expression and inflammatory mediator release by commonly used surgical suture materials: an experimental in vitro study

Fig. 1

a Gene Expression Results. Relative gene expression of five pro-inflammatory markers (four cytokines (IL-1β, IL-1α, TNFα and IL-8) and one cell surface marker (CCR7)) from THP-1 cells in contact with a variety of suture materials were measured by RT-PCR on days 1, 3 and 5. The most representative independent biological repeat is reported ± SEM. Statistical analysis was performed using two-way ANOVA and post-hoc Dunnett’s test (*p < 0.05, **p < 0.01, ***p < 0.001), ****p < 0.0001). b Gene Expression Results. Relative gene expression of three anti-inflammatory markers (two cytokines (TGFβ1 and IL-1RA) and one cell surface marker (CD163)) from THP-1 cells in contact with a variety of suture materials were measured by RT-PCR on days 1, 3 and 5. The most representative independent biological repeat is reported ± SEM. Statistical analysis was performed using two-way ANOVA and post-hoc Dunnett’s test (*p < 0.05, **p < 0.01, ***p < 0.001), ****p < 0.0001)

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Patient Safety in Surgery

ISSN: 1754-9493