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Table 2 Univariate analysis of risk factors associated with treatment failure of PTOa

From: Predisposing factors for recurrence of chronic posttraumatic osteomyelitis: a retrospective observational cohort study from a tertiary referral center in Brazil

Characteristics

Failure No. (%)

(N = 38)

Remission No. (%)

(N = 154)

P valuec

Demographic data

 Age (median [range]) (yr)

70 (16 – 88)

40.5 (11 – 86)

<0.001

 ≤40 years

9 (23.6)

77 (50)

 

 41 – 60 years

6 (15.8)

55 (35.7)

 

 61 – 80 years

14 (37)

20 (13)

 

  ≥ 80 years

9 (23.6)

2 (1.3)

 

 Male sex (no. [%])

19 (50)

113 (73.4)

0.005

 Household activities (no. [%])

20 (52.6)

39 (25.3)

0.001

Comorbidities (no. [%])

 Smoking

11 (29.0)

50 (32.5)

0.676

Fall from height (no. [%])

23 (60.5)

34 (22.0)

<0.001

Grade-III open fracture (no. [%])

6 (15.8)

30 (19.5)

0.602

Admission to surgery t >3h (no. [%])

36 (94.7)

139 (90.2)

0.532

>1 surgery debridement (no. [%])

23 (60.5)

54 (35.0)

0.004

Need for blood transfusion (no. [%])

23 (60.5)

43 (28.0)

<0.001

Lower limb fractures (no. [%])

37 (97.3)

116 (75.3)

0.002

Bipolar hip prosthesis (no. [%])

8 (21.0)

5 (3.2)

<0.001

ASA score

 ASAb I - II (no. [%])

30 (79.0)

145 (94.1)

0.007

 ASA III - IV (no. [%])

9 (12.3)

8 (7.3)

Chronic osteomyelitis (no. [%])

16 (42.1)

84 (54.5)

0.169

Staphylococcus aureus culture (no. [%])

25 (13%)

79 (41.1%)

0.010

Streptococcus sp. culture (no. [%])

4 (10.5)

4 (2.6)

0.051

Enterococcus sp. culture (no. [%])

8 (21.1)

14 (9.1)

0.048

Escherichia coli culture (no. [%])

6 (15.8)

8 (5.2)

0.036

Pseudomonas aeruginosa culture (no. [%])

17 (44.7)

14 (9.1)

<0.001

Acinetobacter baumannii culture (no. [%])

10 (26.3)

13 (8.4)

0.005

  1. PTOa: posttraumatic osteomyelitis
  2. ASAb: American Society of Anesthesiologists
  3. cPatient characteristics were summarized as frequencies and percentages or median and compared using the Pearson Chi-Square test or Fisher’s exact test as appropriate to nominal variables and Mann–Whitney Test or T-Test as appropriate to continuous variables. All tests were two sided, and P values of <0.05 were considered statistically significant