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Table 1 Medications and dosages in opioid-based vs. opioid-free anesthesia

From: Opioid-free anesthesia: the next frontier in surgical patient safety

Opioid-based

Opioid-free

 

Induction (boluses)

Propofol 1.5–2 mg/kg

Propofol 1 mg/kg

Fentanyl 1–5 μg/kg

Dexmedetomidine 0.2–0.5 μg/kg (incremental dosages)

Versed 1–5 mg

Ketamine 0.25–0.5 mg/kg

Lidocaine 1.5 mg/kg

Lidocaine 2 mg/kg

 

Toradol 15–30 mg

 

Maintenance Infusion (“McLott Mix”)

 

Dexmedetomidine 0.4 μg/kg/hr

 

Ketamine 0.3 mg/kg/hr

 

Lidocaine 2 mg /kg/hr

 

Magnesium 10 mg /kg/hr