The risk of intra-urethral Foley catheter balloon inflation in spinal cord-injured patients: Lessons learned from a retrospective case series
© Vaidyanathan et al. 2016
Received: 26 February 2016
Accepted: 30 April 2016
Published: 21 May 2016
Inflating the balloon of Foley catheter in urethra is a complication of urethral catheterisation. We report five patients in whom this complication occurred because of unskilled catheterisation. Due to lack of awareness, the problem was not recognised promptly and patients came to harm.
A tetraplegic patient developed pain in lower abdomen and became unwell after transurethral catheterisation. CT pelvis revealed full bladder with balloon of Foley catheter in dilated urethra.
Routine ultrasound examination in an asymptomatic tetraplegic patient with urethral catheter drainage, revealed Foley balloon in the urethra. He was advised to get catheterisations done by senior health professionals.
A paraplegic patient developed bleeding and bypassing after transurethral catheterisation. X-ray revealed Foley balloon in urethra; urethral catheter was changed ensuring its correct placement in urinary bladder. Subsequently, balloon of Foley catheter was inflated in urethra several times by community nurses, which resulted in erosion of bulbous urethra and urinary fistula. Suprapubic cystostomy was performed.
A tetraplegic patient developed sweating and increased spasms following urethral catheterisations. CT of abdomen revealed distended bladder with the balloon of Foley catheter located in urethra. Flexible cystoscopy and transurethral catheterisation over a guide-wire were performed. Patient noticed decrease in sweating and spasms.
A paraplegic patient developed lower abdominal pain and nausea following catheterisation. CT abdomen revealed bilateral hydronephrosis and hydroureter and Foley balloon located in urethra. Urehral catheterisation was performed over a guide-wire after cystoscopy. Subsequently suprapubic cystostomy was done.
Spinal cord injury patients are at increased risk for intra-urethral Foley catheter balloon inflation because of lack of sensation in urethra, urethral sphincter spasm, and false passage due to previous urethral trauma. Education and training of doctors and nurses in proper technique of catheterisation in spinal cord injury patients is vital to prevent intra-urethral inflation of Foley catheter balloon. If a spinal cord injury patient develops bypassing or symptoms of autonomic dysreflexia following catheterisation, incorrect placement of urethral catheter should be suspected.
KeywordsSpinal cord injury Foley catheter Urethral catheterisation
In 2010, we proposed that incorrect placement of a Foley catheter leading to inflation of Foley balloon in urethra in a spinal cord injury patient should be declared as a “never event” . Although several advances have been made in management of spinal cord injury patients during this decade, we continue to see this complication of Foley catheter balloon inflation in urethra in spinal cord injury patients. We present five patients, in whom we detected this complication between 2012 and 2015 when these patients visited spinal injuries centre; it is possible that some other patients had developed this complication which went either undetected in the community or managed symptomatically in general hospitals without being recognised. The aim of this report is to raise awareness among health professionals in order to prevent intra-urethral Foley catheter balloon inflation in spinal cord injury patients and thereby reduce harm to patients.
A 61-year-old male patient with tetraplegia attended a hospital as he was bypassing the indwelling urethral catheter. Transurethral catheterisation was performed by a health professional in the community. But, the catheter did not drain urine satisfactorily. The patient developed severe pain in lower abdomen; subsequently, he started getting pain in both kidneys as well; he developed loss of appetite and felt sick. He came to spinal unit after two weeks. On clinical examination, a long segment of Foley catheter was found to be lying outside penis. The patient was clear that the same length of catheter was lying outside his penis right from the time of insertion. Blood tests: C-reactive protein: 222.4 mg/L; urea: 1.8 mmol/L; Creatinine: 39umol/L. Clinical diagnosis was misplacement of urinary catheter in urethra with urosepsis.
Urethral catheter was removed; a Foley catheter with 20 ml balloon was inserted in the urinary bladder as a 10 ml balloon might slip through dilated bladder neck into urethra; turbid urine was drained. This patient was prescribed 160 mg of gentamicin followed by Ciprofloxacin by mouth. Three days later, the catheter got blocked; a district nurse changed the catheter; but inserted a Foley catheter with 10 ml balloon. The catheter did not drain urine satisfactorily and the patient came to spinal unit. On clinical examination, it was obvious that the catheter had been misplaced in the urethra, either got curled itself in dilated urethra during insertion or slipped into urethra subsequently. The Foley catheter had a radio-opaque marker; therefore, X-ray of pelvis was taken to find out precise location of the tip of the catheter. X-ray of pelvis revealed the tip of Foley catheter in the urethra. The catheter was removed and a Foley catheter with 20 ml balloon was inserted. The patient was reviewed after eleven days. The catheter was draining fine and patient was well.
A 66-year-old, British Caucasian male, sustained hyperextension injury to neck in a bicycle accident in 2011. He developed tetraplegia at C-5. This patient had been managing his bladder by indwelling urethral catheter. Urethral catheter was being changed by district nurses. About 29 months after spinal injury, this patient came to spinal unit for routine ultrasound examination of urinary tract. Ultrasound revealed normal appearance of the kidneys, with no renal calculi or hydronephrosis; balloon of Foley catheter was not seen within the bladder. Urinary catheter had been misplaced, with catheter balloon in the urethra and not within the urinary bladder. Urethral catheter was removed and a size 14 French Foley catheter was inserted by a senior and experienced health professional. The patient was informed about incorrect placement of urethral catheter. We discussed with the patient precautions to be observed while inserting a catheter in order to ensure that the catheter was positioned correctly within the urinary bladder. He was advised to get transurethral catheterisations by senior health professionals. Follow-up ultrasound scan revealed the balloon of the catheter located in the bladder lumen which was otherwise empty.
Risk factors for intra-urethral Foley catheter balloon inflation in spinal cord-injured patients
Lack of sensation in urethra as a result of spinal cord injury: when the balloon is inflated in urethra, a spinal cord injury patient may not complain of pain or discomfort; so the health professional may not realise that catheterisation has gone wrong.
Trauma to urethra during previous catheterisations resulting in urethral false passage
Spasm of pelvic floor muscles and urethral sphincter which prevent the catheter from entering the bladder and leads to curling of Foley catheter in urethra
Altered anatomy of lower urinary tract due to surgery in the past e.g. bladder neck resection, sphincterotomy.
Once the balloon of Foley catheter is inflated in urethra, the prostate-membranous urethra becomes dilated; during subsequent catheterisations, the tip of catheter gets doubled back in urethra instead of going straight into the bladder; thus the problem is likely to recur because of chronic dilatation of prostate-membranous urethra.
Another reason is the habit of using spinal cord injury patients, especially elderly persons, for “practising clinical skills” by student nurses and trainee doctors, be it administration of intramuscular injection, or transurethral catheterisation. Unless this custom is halted, spinal cord injury patients will continue to suffer from iatrogenic complications and receive substandard clinical care .
Clinical features of intra-urethral Foley catheter balloon inflation in spinal cord-injured patients
If a spinal cord injury patient develops bypassing, symptoms of autonomic dysreflexia (headache, profuse sweating and flushing of the skin above the level of the lesion, goose bumps below the level of the lesion, blurred vision, nasal congestion) or increased spasms following transurethral catheterisation, incorrect placement of urethral catheter should be suspected.
Symptoms manifested by the five patients in this case series were:
Patient number 1 developed bypassing, kidney pain and became unwell.
Patient number 4 developed urethral bleeding, increased spasms and sweating following change of urethral catheter.
Patient number 5 developed urine infection and CT revealed bilateral hydronephrosis and hydroureter.
Patient number 2, in whom the Foley catheter balloon had been inflated in urethra for weeks, remained asymptomatic. Incorrect placement of urethral catheter was detected during routine ultrasound scan of urinary tract.
In patient number 3, recurrent inflation of the Foley balloon in urethra resulted in erosion of urethra, breakdown of the skin in perineum and urinary fistula.
The wide spectrum of symptoms of intra-urethral inflation of Foley catheter balloon inflation is summarised below:
Bypassing and unsatisfactory drainage through the catheter
Lower abdominal pain, kidney pain
Clinical features of autonomic dysreflexia commonly manifesting as sweating, headache and increased spasms
Urine infection and urosepsis
Bilateral hydronephrosis and hydroureter leading to kidney injury
Erosion of urethra, urethral fistula
Skin breakdown in perineum where the Foley balloon had been kept inflated for prolonged period.
Diagnosis of intra-urethral Foley catheter balloon inflation in spinal cord-injured patients
When a spinal cord injury patient with indwelling urethral catheter develops bypassing or symptoms of autonomic dysreflexia after transurethral catheterisation, incorrect placement of catheter should be considered. Irrigating the catheter for isovolumetric return and physical examination assessing the length of exposed catheter are often sufficient to diagnose the problem. If the balloon of a Foley catheter is inflated in urethra, an excessive length of catheter will remain outside the penis. This sign is termed “long catheter sign” . If initial bedside assessment is inconclusive, imaging studies should be carried out to locate the position of Foley balloon and tip of catheter. Imaging studies are useful to document what has happened. Ultrasound scan may not be technically satisfactory in some patients because of body habitus; in some others, it may not be possible to see the Foley catheter balloon because urinary bladder is empty or under-filled. CT images showing the Foley catheter balloon inflated in urethra helps to establish the diagnosis; aids greatly in teaching and learning; provides incontrovertible evidence for subsequent case discussion e.g. root cause analysis of this serious adverse event; retraining the involved health professional, dealing with patient complaint and litigation claims; and most importantly identifying the patient as a high-risk case for recurrence of this complication. While carrying out ultrasound or CT scan of urinary tract in patients with urethral catheter drainage, proximal urethra should be scanned if Foley balloon is not visible inside the urinary bladder. Certainly CT scan and MRI should not be routinely utilised to confirm catheter placement as these tests are costly.
Prevention of intra-urethral Foley catheter balloon inflation in spinal cord-injured patients
Education and Training
Education and training of doctors on proper insertion of catheter is important to prevent misplacement of transurethral catheter. Health professionals should adhere to the technique of proper insertion of transurethral catheter in spinal cord injury patients at all times: adequate lubrication, avoid use of size 12CH in difficult cases due to risk of curling of the catheter, insert catheter to the hub, inflate balloon without resistance (an experienced person should be able to tell if the balloon is inflating properly), pulling the catheter back to feel it catch on the bladder neck after balloon inflation, and flushing the catheter with 50 ml of 0.9 % sodium chloride is a quick and easy test to help detect problems (i.e. if it bypasses right out the urethra, or won’t inject, the catheter is probably not positioned correctly.) Urethral trauma from inadvertent inflation of catheter balloon in the urethra during catheterization may be prevented by the use of a safety syringe when this syringe becomes available for routine use .
Transurethral catheterisaion should be performed by experienced health professionals in high risk patients
Once the balloon of Foley catheter is inflated in urethra, during subsequent catheterisations, the problem is likely to recur because of chronic dilatation of urethra and sphincter spasm. Therefore, urethral catheterisation should be performed in such high risk patients by senior, experienced health professionals both in the hospital and in the community in order to prevent recurrence of the same complication.
Choice of Foley catheter balloon size to prevent this complication
Depending on the anatomy of urethra and bladder neck in a spinal cord injury patient, appropriate Foley balloon size should be used for transurethral catheterisation. For example, in a patient with wide open bladder neck, a 20 ml balloon Foley catheter is preferable to a standard 10 ml balloon catheter in order to prevent the catheter from slipping into urethra. In case 1, the bladder neck and prostatic urethra became dilated as a result of repeated episodes of inflating Foley balloon in urethra. After insertion of a size 20 ml balloon Foley catheter, transurethral catheter did not slip into urethra.
Avoid transurethral catheter drainage
Intra-urethral Foley catheter balloon inflation can be prevented if urethral catheter drainage is avoided altogether: e.g. by carrying out intermittent catheterisations either by the patient or by carers. Suprapubic cystostomy will help to prevent complications of transurethral catheterisation, but suprapubic cystostomy may lead to different set of problems albeit rarely [5–7].
Conclusions and Take home message
Spinal cord injury patients are at increased risk for inflation of Foley catheter balloon in urethra because of lack of sensation in urethra, urethral sphincter spasm, and previous urethral trauma resulting in false passage.
Education and training of doctors and nurses in proper technique of catheterisation in spinal cord injury patients is vital to prevent inflation of Foley catheter balloon in urethra.
If a spinal cord injury patient develops bypassing or symptoms of autonomic dysreflexia following transurethral catheterisation, incorrect placement of urethral catheter should be suspected.
A simple catheter irrigation and physical examination assessing the length of exposed catheter are often sufficient to diagnose the problem. If initial bedside assessment is inconclusive, imaging studies should be carried out to locate the position of Foley balloon and tip of catheter. Imaging studies are useful to document what has happened.
Intra-urethral Foley catheter balloon inflation can be prevented if transurethral catheter drainage is avoided altogether.
Consent for publication
All patients gave consent for publication of the Case report and any accompanying images.
The authors are most grateful to Ms Anna Cracknell, Hollister UK, and Hollister UK for the valuable help in payment of article processing fee for this manuscript.
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- Vaidyanathan S, Soni BM, Hughes PL, Singh G, Oo T. Severe ventral erosion of penis caused by indwelling urethral catheter and inflation of Foley balloon in urethra-need to create list of “never events in spinal cord injury” in order to prevent these complications from happening in paraplegic and tetraplegic patients. Adv Urol. 2010;461539:Epub 2010 Jun 27.Google Scholar
- Vaidyanathan S, Singh G, Soni B, Hughes P, Pulya K. Substandard urological care of elderly patients with spinal cord injury: an unrecognized epidemic? Patient Saf Surg. 2014;8(1):4. doi:https://doi.org/10.1186/1754-9493-8-4.View ArticlePubMedPubMed CentralGoogle Scholar
- Vaidyanathan S, Hughes PL, Oo T, Soni BM. Long catheter sign: a reliable bedside sign of incorrect positioning of foley catheter in male spinal cord injury patients. Cases J. 2008;1(1):43. doi:https://doi.org/10.1186/1757-1626-1-43.View ArticlePubMedPubMed CentralGoogle Scholar
- Davis NF, Mooney RO, Cunnane CV, Cunnane EM, Thornhill JA, Walsh MT. Preventing Urethral Trauma from Inadvertent Inflation of Catheter Balloon in the Urethra during Catheterization: Evaluation of a Novel Safety Syringe after Correlating Trauma with Urethral Distension and Catheter Balloon Pressure. J Urol. 2015;194:1138–45. doi:https://doi.org/10.1016/j.juro.2015.02.083. Epub 2015 Feb 21.View ArticlePubMedGoogle Scholar
- Sumiya T. Hypertensive intracerebral hemorrhage due to autonomic dysreflexia in a young man with cervical cord injury. J UOEH. 2013;35:159–64.View ArticlePubMedGoogle Scholar
- Adeyemo B, Makovitch S, Foo D. A peculiar complication of suprapubic catheterization: recurrent ureteral obstruction and hydronephrosis. J Spinal Cord Med. 2013;36:166–9. doi:https://doi.org/10.1179/2045772312Y.0000000080.View ArticlePubMedPubMed CentralGoogle Scholar
- Ito H, Arao M, Ishigaki H, Ohshima N, Horita A, Saito I, Hirai K. A case of squamous cell carcinoma arising from a suprapubic cystostomy tract. BMC Urol. 2011;11:20. doi:https://doi.org/10.1186/1471-2490-11-20.View ArticlePubMedPubMed CentralGoogle Scholar